Diphenhydramine dosage

Diphenhydramine Citrate: 38 to 76 mg orally every 4 to 6 hours as needed -Maximum dose: 456 mg/day Diphenhydramine Hydrochloride: 25 to 50 mg orally every 4 to 6 hours as neede To give the proper dose of diphenhydramine, you must know your child's current weight. Age limit: Do . NOT. use if child is under 12 months of age unless you consult your healthcare provider. Avoid using in children under 6 years of age unless instructed by a healthcare provider. Dosage: Find your child's weight in the top row of the dosage table

Diphenhydramine is used to treat sneezing, runny nose, watery eyes, hives, skin rash, itching, and other cold or allergy symptoms. Diphenhydramine is also used to treat motion sickness, to induce sleep, and to treat certain symptoms of Parkinson's disease. Diphenhydramine may also be used for purposes not listed in this medication guide. Warning Usual Adult Dose for Pain. Acetaminophen 325 mg/diphenhydramine 12.5 mg: 2 tablets orally every 4 to 6 hours as needed. Maximum dose: 8 tablets in 24-hours. Acetaminophen 500 mg/diphenhydramine 12.5 mg: 2 tablets orally every 6 hours as needed. Maximum dose: 6 tablets in 24-hours Dose every 6 hours: Dose for hives and/or itching. In general, once hives have started, you should continue regular dosing until there have not been hives for the entire day

Nonanticholinergic antihistamines should be considered first for treatment of allergic reaction (Beers criteria); use of diphenhydramine in acute treatment of severe allergic reaction may be.. Diphenhydramine dosage. Applies to the following strengths diphenhydramine: 50 mg/mL; 12.5 mg; 25 mg; 12.5 mg/5 mL; 50 mg; 10 mg/mL; 19 mg; 6.25 mg/5 mL; 25 mg/5 mL; 50 mg/30 mL; 6.25 mg/mL. Usual Adult Dose for Insomnia. Diphenhydramine Citrate: 76 mg orally once a day at bedtim 10 to 50 mg intravenously at a rate generally not exceeding 25 mg/min, or deep intramuscularly, 100 mg if required; maximum daily dosage is 400 mg. How is Diphenhydramine Injection Supplied. Diphenhydramine Hydrochloride Injection, USP in parenteral form is supplied as Adult: 25-50 mg 3 or 4 times daily. Max: 300 mg daily. For prevention of motion sickness, administer 30 minutes before exposure to motion. Child: 2-6 years 6.25 mg 4-6 hourly; 6-12 years 12.5-25 mg 4-6 hourly; >12 years Same as adult dose. For prevention of motion sickness, administer 30 minutes before exposure to motion hay fever and allergies - diphenhydramine comes as 25mg and 50mg tablets. The usual dose is 25mg or 50mg, taken 3 or 4 times a day. Try to space your doses evenly throughout the day. insect bites, stings and eczema - diphenhydramine comes as a cream which you use once or twice a day

Diphenhydramine Dosage Guide with Precautions - Drugs

A single oral dose of diphenhydramine hydrochloride is quickly absorbed with maximum activity occurring in approximately one hour. The duration of activity following an average dose of diphenhydramine hydrochloride is from four to six hours. Diphenhydramine is widely distributed throughout the body, including the CNS These dosages are suggested by the manufacturer: 2. Extrapyramidal reaction: 25 to 50 milligrams (mg) orally 3 to 4 times a day. Insomnia: 50 mg orally once a day at bedtime. Motion sickness: 25 to 50 mg 3 to 4 times a day. Allergic rhinitis: 25 to 50 mg orally every 4 to 6 hours as needed Maximum dose: 300 mg/day According to user reports, diphenhydramine has a non-linear dose-response, meaning the effects do not correspond directly with the dose. Lower doses produce a body high effect, while higher doses produce a state of delirium in which the user sees and hears fully-formed, extremely convincing hallucinations

Do not take more than 6 doses in 24 hours. Use only as directed. Do not take more than 6 doses in 24 hours. Use only as directed Diphenhydramine dosage. The information provided is no substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment. How is the dose of diphenhydramine for older persons? Here is a dose of diphenhydramine for older persons: Older persons doses for extrapyramidal symptoms. Parenteral: 10-50 mg IV or IM as needed

For severe symptoms the critical dose limit was 1.0 g DPHM. Although the frequency of delirium/psychosis remained constant or even decreased, coma and seizures were significantly (p<0.05) more frequent in the >1.5-g compared with the 1.0- to 1.5-g-dose group For adults and teens, the diphenhydramine dosage is 25 to 50 mg every 4 to 6 hours. The maximum amount you should take in one day is 300 mg. Keep in mind, taking higher doses can increase the risk of side effects, including drowsiness Example dosage information of diphenhydramine includes: An adult dose for itching of 25 mg to 50 mg, taken by mouth, every 4-6 hours as needed but no more than 300 mg in 24 hours Eliglustat: (Major) In extensive or intermediate CYP2D6 metabolizers (EMs or IMs), coadministration of scheduled diphenhydramine and eliglustat requires dosage reduction of eliglustat to 84 mg PO once daily during the course of antihistamine treatment; however coadministration of eliglustat with both diphenhydramine and a strong or moderate CYP3A inhibitor is contraindicated

Diphenhydramine Uses, Dosage & Side Effects - Drugs

  1. e Injection: Motion sickness. Adult Dosage: 10-50mg IV or deep IM; max 400mg/day. Children Dosage: Neonates: not recommended. Others: 5mg/kg per day in 4 divided.
  2. e Overdose - Symptoms, Dosage, Effects, Diagnosis and Treatments 27/06/2012 18/12/2017 ad
  3. e is part of a class of medications called antihista
  4. e (Benadryl) Dose Table Diphenhydra
  5. e / ad
  6. e) you can give your dog. You should ad

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Acetaminophen / Diphenhydramine Dosage Guide with


Generic Name : Diphenhydramine Pronunciation : dye fen hye' dra meen Latest prescription information about Diphenhydramine. Learn how to pronounce the drug's name, its indications, dosage, how to. Diphenhydramine kinetics following intravenous, oral, and sublingual dimenhydrinate administration. Eight healthy volunteers received 50 mg of dimenhydrinate, a theoclate salt of diphenhydramine, orally, sublingually, and intravenously on three separate occasions in random sequence

High doses of DPH just ain't my thing lol. If you're looking for a psychosis type of high then go for it. Low dose DPH (Simply Sleep) (50mg-100mg) for me settles in real nice with some excedrin for some odd reason, gives a really pleasant sedative effect. I went to CVS and bought one box of benadryl allergy which contains 24 capsels with 25 mg of Diphenhydramine in each one. At about 9:00 that night, I took 20 capsels. I really don't remember much from that night, just feeling really heavy, and slight perceptional changes

Benadryl, Nytol (diphenhydramine) dosing, indications

  1. es for Integumentary Disease. Antihista
  2. Generic name in brackets. 1000 milligrams (mg.) = 15 grains (gr.) = 1 gram (gm.) Nitschke and Stewart 3 state that Propoxyphene commonly comes in 100mg tablets, and state an MLD of 10 grams (100 tablets of 100 mg), taken together with long acting sleeping tablets like Oxazepam.. Nitschke and Stewart 3 state that the MLD of Amitriptyline is 5gm, and the most commonly supplied dosage is 50mg.
  3. e (Benadryl) Turbo Orgasm ^10: Anonymous: Diphenhydra

Diphenhydramine - Uses, Dosage, Side Effects, Overdos

  1. e) ® Allergy Kapseals® Capsules
  2. e Paediatric Syrup(Per 5 mL Diphenhydra
  3. The recommended dose of ZzzQuil is 50 mg at bedtime when needed, or as a person's doctor directs. ZzzQuil is available in both liquid and capsule forms. For the liquid form, a single 50 milligram..
  4. e or placebo, given intravenously 3
  5. WebMD - Better information. Better health
  6. 1 tablet. 38 to 49 lbs. 7.5 mL. 1 tablet. *every 4-6 hours. *every 4-6 hours. It's also important to not give too many doses within a certain time period. — no more than six doses in a 24.
  7. Your dosage will depend on your medical condition, age, and other factors. A typical dosage for adults and children ages 12 and older is one to two tablets every four to six hours

Diphenhydramine Injection - FDA prescribing information

  1. e is based on the age, medical condition, and response to treatment. The dosage should not be increased and the medication should not be taken more often than directed. The usual dosage* for different conditions is: Hay fever and allergies - The usual dose is 25mg or 50mg, taken 3 or 4 times a day
  2. e (e.g. Benadryl™) is a medication that is used to treat allergic reactions. As in the case of any medication, the right dosage must be used to ensure the optimum effect with a
  3. e) usually is taken every 6 hours. It generally lasts 6-8 hours. Other factors include how big a dose was taken, and how man..
  4. e for anxiety is that it hasn't been evaluated at multiple doses. As was already mentioned, 25 mg diphenhydra
  5. e tablets are 25 mg, which is the size used for a 25-pound dog. But the safest way to give the proper dose is to ask your veterinarian. In addition, many formulations are combined with other medications such as Tylenol, so make sure Benadryl tablets contain only diphenhydra
  6. e Dosage Table (eg, Benadryl) (Antihista

Diphenhydramine: Indication, Dosage, Side Effect

Indivduals over the age of 60 years are especially sensitive to the sedating and anticholinergic effects of diphenhydramine, and the dose should be reduced. A common regimen for treating adult allergic reaction is 25-50 mg every 4-6 hours not to exceed 300 mg daily. Insomnia is treated with 50 mg taken 30 minutes before bedtime A detailed look into what a lower recreational dose of DPH can provide.Diphenhydramine (150mg, 175mg, 250mg) & Cannabis Diphenhydramine (DPH) Low Dosage E.. Diphenhydramine HCl (Benadryl) Information and dosage chart What is diphenhydramine HCl? Diphenhydramine HCl is an antihistamine, a type of medicine that prevents allergy symptoms. These symptoms include sneezing, runny nose, itching, watery eyes, and rashes or hives (skin welts or raised Or in other words: 10 milligrams per dose (given 2 to 3 times a day) for dogs 30 lbs or smaller, 25 mg per dose for dogs which are between 30 to 50 lbs and 50 mg per dose for dogs 50 lbs or over. The world would be a nicer place if everybody had the ability to love as unconditionally as a dog. — M. K. Clinto Diphenhydramine hydrochloride has been reported to be excreted in breast milk and thus, use of diphenhydramine hydrochloride in lactating mother is not recommended. Precautions & Warnings Caution should be exercised with patients in whom drowsiness is undesirable e.g., drivers, machine operators

The correct dosage of diphenhydramine for dogs depends on their weight. A small dog will need much less than a big dog to receive the same positive effects. According to the Merck Veterinary.. Find everything you need to know about Tylenol PM (Acetaminophen And Diphenhydramine), including what it is used for, warnings, reviews, side effects, and interactions. Learn more about Tylenol PM.

Diphenhydramine (including Nytol Original & Histergan

  1. e) oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings
  2. e Injection) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources
  3. e Dosage. For diphenhydra
  4. e hydrochloride should not be used in neonates and premature infants (see CONTRAINDICATIONS). Diphenhydra

Diphenhydramine Oral Solution - FDA prescribing

Diphenhydramine is an antihistamine that is used to treat sneezing, runny nose, watery eyes, hives, skin rash, itching, and other cold or allergy symptoms. Diphenhydramine is also used to treat motion sickness, to induce sleep, and to treat certain symptoms of Parkinson's disease. Diphenhydramine sleep aid medicine is not for use in children younger than 12 years old If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first. Diphenhydramine Topical has no listed severe interactions with other drugs Diphenhydramine hydrochloride in the injectable form is indicated when the oral form is impractical. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. DOSAGE SHOULD BE INDIVIDUALIZED ACCORDING TO THE NEEDS AND THE RESPONSE OF THE PATIENT Diphenhydramine HCl 25 mg. Diphenhydramine HCl 25 mg. Close. Purpose. Antihistamine. Antihistamine. Close. Uses. temporarily relieves these symptoms due to hay fever or other upper respiratory allergies: runny nose - itching of the nose or throat - itchy, watery eyes - sneezing - temporarily relieves these.

Maximum daily dosage not to exceed 300 mg. For physicians who wish to calculate the dose on the basis of body weight or surface area, the recommended dosage is 5 mg/kg/24 hours or 150 mg/m2/24 hours. Data are not available on the use of diphenhydramine hydrochloride as a nighttime sleep-aid in children under 12 years Diphenhydramine is used to treat allergies, insect bites and stings and other causes of itching. It is also used for its sedative and antiemetic effects in treatment of travel anxiety, and for its antitussive effect in cases of coughs. Dosage and Administratio

Diphenhydramine is a type of medicine called an antihistamine. It is used in some allergy and sleep medicines. Overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose. This article is for information only. DO NOT use it to treat or manage an actual overdose Diphenhydramine - Get up-to-date information on Diphenhydramine side effects, uses, dosage, overdose, pregnancy, alcohol and more. Learn more about Diphenhydramine benadryl dosage chart for adults For Benadryl, talk to the pharmacist where you got it. May 12, 2010 I have to buy some anti-allergic drugs like Claritin or Benadryl. Even though they will not be able to become warriors for the weekend they can be just once. Procedures and products are very interesting reviews, because [ Benadryl Dosage for Dog. The basic dose for oral Benadryl is 1 mg per pound of dog's body weight, given 2-3 times a day. The majority of drug store diphenhydramine tablets are 25 mg, which is the size used for a 25 pound dog. Constantly double check the dose before providing an over the counter medication In general, diphenhydramine is active for between four and six hours and about half of it is removed in between four and eight hours. Nevertheless, morning side effects such as residual sleepiness or hangover can occur, though this typically improved after about four nights of use. 2. In a study of older adults, diphenhydramine reduced.

Benadryl dosage for cats. Many vets will recommend a quarter of an adult sized dosage of Benadryl or half of a child sized dosage. This equates to about 12.5mg. To be even more precise, many vets recommend about 1mg of Benadryl for every pound the cat weighs. So a ten pound cat would require 10mg of Benadryl The duration of activity following an average dose of Diphenhydramine hydrochloride is from four to six hours. ADULTS: 25 to 50 mg three or four times daily. The nighttime sleep-aid dosage is 50 mg at bedtime. CHILDREN: (over 20 lbs.): 12.5 to 25 mg three or four times daily. Maximum daily dosage not to exceed 300 mg For Benadryl in liquid form the dosage translates to 0.4ml for every 1lb of the body weight of your dog. So again: if your dog weighs 80 pounds, this means 32ml every 8 hours. Here on the right is a table to make it easy for you to translate the body weight of your dog into the proper dosage of Benadryl. This dosage is not set in stone though Diphenhydramine Hydrochloride Injection is indicated when the oral form is impractical. DOSAGE SHOULD BE INDIVIDUALIZED ACCORDING TO THE NEEDS AND THE RESPONSE OF THE PATIENT. Pediatric Patients, Other Than Premature Infants and Neonates 5 mg/kg/24 hours or 150 mg/m/24 hours. Maximum daily dosage is 300 mg. Divide into four doses

Diphenhydramine: Uses, Side Effects, Dosages, Precaution

Diphenhydramine should not be used in neonates and premature infants (see CONTRAINDICATIONS). Diphenhydramine may diminish mental alertness, or in the young pediatric patient, cause excitation. Overdosage may cause hallucinations, convulsions or death (see WARNINGS and OVERDOSAGE). See also DOSAGE AND ADMINISTRATION section daily dosage is 300 mg. Divide into four doses, admin-istered intravenously at a rate generally not exceed-ing 25 mg/min, or deep intramuscularly. Adults: 10 mg to 50 mg intravenously at a rate.. The typical starting dosage of Benadryl for adults is 25mg. This is usually effective in treating allergies as well as for providing sedation. Smaller adults or females often find half of this dosage to be effective as well at 12.5 mg. Those who take Benadryl during the day and wish to avoid drowsiness may wish to start at lower doses Diphenhydramine is available in 12.5 mg, 25 mg, and 50 mg tablets, as well as a 12.5 mg/5 mL suspension. The injectable version is available in 10 mg/mL and 50 mg/mL concentrations Recommended dosage The dosage of diphenhydramine must be adjusted according to the needs of individuals and their responses. Adults are generally given 25-50 mg orally, three to four times daily. Diphenhydramine may be administered through a vein or injected deep within a muscle

Benadryl Dosage - BabyCenter

Diphenhydramine - PsychonautWik

Diphenhydramine (Benadryl) Dose Table Child's weight (pounds) 20-24 25-37 38-49 50-99 100+ lbs. Liquid 12.5 mg/ 5 milliliters (mL) 4 5 7.5 10 -- mL Liquid 12.5 mg/ 1 teaspoon (tsp) ¾ 1 1½ 2 -- tsp Chewable 12.5 mg -- 1 1½ 2 4 tablets Tablets 25 mg -- ½ ½ 1 2 tablets Capsules 25 mg -- -- -- 1 2 cap Antihistamine & antiparkinsonism 1 cap every 6 hr. Nighttime sleeping aid 1 cap 20 min before going to bed.Antitussive 1 cap every 8 hr. Motion sickness 1 cap 30 min before exposure to motion. Subsequent doses may be given every 6 hr at bedtime. Max: 300 mg in 24 hr. Renal impairment Dosage intervals: 6-12 hr Diphenhydramine (pill / tablet) T+ 24:00: 350 mg: oral: Diphenhydramine (pill / tablet Note: Some internet sources equate Diphenhydramine (Benadryl) and Dimenhydrinate (Dramamine). They are actually different chemicals, with different effects and dosage ranges. The chart below shows approximate recreational dosages for pure diphenhydramine, measured in milligrams (mg). Oral Diphenhydramine Dosages (Recreational) Threshold 10m Benadryl is a brand of various antihistamine medications used to stop allergies, whose content varies in different countries, but which includes some or no combination of diphenhydramine, acrivastine, and cetirizine.. It is sold by Johnson & Johnson.Benadryl is used to relieve allergy symptoms such as sneezing, itching, runny nose, rash, and hives


I can shed some light on the planking. I've seen it. My ex wife recently attempted suicide by Diphenhydramine. When I got to her, she was still able to talk and walk. She took between 300 - 500 pills. Time from consumption to clinical death was around an hour Diphenhydramine (Benadryl, Aleve PM, others). Diphenhydramine is a sedating antihistamine. Side effects might include daytime drowsiness, dry mouth, blurred vision, constipation and urinary retention. Doxylamine succinate (Unisom SleepTabs). Doxylamine is also a sedating antihistamine. Side effects are similar to those of diphenhydramine. Melatonin Diphenhydramine pharmacokinetics in adults have been reported for single doses of 25 and 50 mg diphenhydramine HCl. 3-6 Following intravenous administration of 50 mg, diphenhydramine pharmacokinetic parameters included a total systemic clearance of 6.16 mL/min/kg, a terminal volume of distribution of 4.54 L/kg, and a terminal exponential half‐life of 8.5 hours. 5 Following oral administration of 50 mg in two studies, diphenhydramine attained maximum concentrations at 2.3 and 2.2 hours, and. Diphenhydramine hydrochloride 1%. Ingredient Purpose: Topical analgesic. Ingredient Name: Zinc acetate 0.1%. Ingredient Purpose: Skin protectant. Inactive Ingredients cetyl alcohol, diazolidinyl urea, methylparaben, polyethylene glycol monostearate 1000, propylene glycol, propylparaben, purified wate

ZzzQuil Alcohol Free Nighttime Sleep-Aid (solution) The

11 Diphenhydramine Side Effects, Rules Of Use, And Dosage

MEASURING the DOSAGE: Syringes and droppers are more accurate than teaspoons. If possible, use the syringe or dropper that comes with the medication. If not, medicine syringes are available at pharmacies. If you use a teaspoon, it should be a measuring spoon A pharmacy may supply magic mouthwash in small containers for individual use or a large container from which a person will pour each dose. The typical administration is about 30 ml every 4-6 hours... Diphenhydramine is available in tablet, liquid or injectable forms. Your dog's weight will determine his daily medication dose. Discuss dosage instructions with your veterinarian carefully, and do not attempt to use this medication on your dog without consulting your veterinarian Diphenhydramine (109) : First Times (2), Alone (16) COPYRIGHTS: All reports are copyright Erowid and you agree not to download or analyze the report data without contacting Erowid Center and receiving permission first. Experience Reports are the writings and opinions of the individual authors who submit them Diphenhydramine Oral solution 12.5mg Drug Medication Dosage information. Learn about the reported side effects, related class drugs, and how these medications will affect your daily lifestyle. Visit cvs.com for more details

Benadryl for dogs (with Safe Dosage Guide)

Dose-dependent toxicity of diphenhydramine overdos

Patients receive ondansetron hydrochloride IV twice daily and saline IV twice daily beginning 30-60 minutes prior to the start of chemotherapy. Patients also receive diphenhydramine hydrochloride, lorazepam, and dexamethasone by continuous infusion pump dosage should be individualized according to the needs and the response of the patient. Pediatric Patients, other than premature infants and neonates 5 mg/kg/24 hr or 150 mg/m2/24 hr. Maximum daily dosage is 300 mg. Divide into four doses, administered intravenously at a rate generally not exceeding 25 mg/min, or deep intramuscularly

How Much Diphenhydramine Can I Take? Diphenhydramine Dosag

Benadryl, or diphenhydramine, is commonly prescribed by vets when a dog is suffering from allergies, or as a preventative measure for motion sickness if you're planning on travelling with your pet. The medication is often sold in 25 mg and 50 mg formulations, for treating dogs the 25 mg formulation is often more suitable Benadryl AH(diphenhydramine): Perennial & seasonal (hay fever) allergic rhinitis; vasomotor rhinitis, allergic conjunctivitis due to inhalant allergens. Dosage/Direction for Use . Adult 50 mg tid-qid. Childn >20 lb 12.5-25 mg tid-qid. Max: 300 mg/day. Base on body wt: 5 mg. Diphenhydramine HCl 25 mg. Ingredient Purpose Antihistamine. Inactive Ingredients carnauba wax, croscarmellose sodium, D&C red no. 27 aluminum lake, dibasic calcium phosphate, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, titanium dioxid Parenteral diphenhydramine is commonly used as adjuvant therapy for acute migraine despite the fact that data supporting this practice do not exist. The investigators propose a randomized double blind study to test the hypothesis that 50mg of intravenous diphenhydramine, when added to standard migraine therapy, will result in a greater rate of sustained headache relief than standard migraine.

Benadryl For Dogs: Dosage, Uses, And Side Effects - DogtimeDiphenhydramine Hydrochloride - patient informationGroundhog Day: 9pmMedical Help: Benadryl

An oral rinse containing the antihistamine diphenhydramine hydrochloride, the topical anesthetic agent lidocaine, and the antacids aluminum hydroxide and magnesium hydroxide (DLA), with potential analgesic and anti-mucositic activities. Upon swishing and gargling with the DLA rinse, the diphenhydramine may provide analgesia; the lidocaine exerts an anesthetic activity which may further relieve. Diphenhydramine HCl 25 mg. Ingredient Purpose Antihistamine. Inactive Ingredients gelatin, glycerin, polyethylene glycol, purified water, and sorbitol Capsules are imprinted with edible dye-free ink. Directions. Take every 4 to 6 hours. Do not take more than 6 doses in 24 hours It comes in 25 milligram (mg) tablets, 25 mg liquid-filled gel capsules, 12.5 mg chewable tablets, and 12.5 mg doses taken as a liquid solution, which is 12.5 mg per teaspoon/5 milliliters (mL). The standard dosages of oral Benadryl are as follows: 5. Age Group. Dose Dosage Forms & Strengths cream . 2% plus zinc acetate 0.1%; 1% plus zinc acetate 0.1%; gel . 2%; spray. 2% plus zinc acetate 0.1%; 2% with menthol 1%; stick. 2% plus zinc acetate 0.1 Diphenhydramine is used to treat sneezing, runny nose, watery eyes, hives, skin rash, itching, and other cold or allergy symptoms. Diphenhydramine is also used to treat motion sickness, to induce sleep, and to treat certain symptoms of Parkinson's disease. Diphenhydramine may also be used for purposes not listed in this medication guide

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